Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Vitellogenin (vtg) was isolated from greenback flounder (Rhombosolea tapirina), rainbow trout, (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar) plasma. The molecular weight of each native molecule, as determined by gel filtration, was 540, 383 and 557 kD respectively. With SDS-PAGE under reducing conditions, rainbow trout vtg dissociated into 1 major subunit (~154 kD), and Atlantic salmo...

متن کامل

Identification of Mycobacterium Tuberculosis Complex, Using Molecular Methods

Abstract Background and Objective: A high level of homogeneity observed within all bacteria in the Mycobacterium tuberculosis complex makes a property that seriously challenges traditional biochemical-based identification methods of these pathogens in the laboratory. The work presented here was conducted to characterize Mycobacterium tuberculosis complex isolates in Golestan, Northern Iran. ...

متن کامل

Symposium: Nutrition, Biochemistry and Molecular Biology of Biotin Cellular Uptake of Biotin: Mechanisms and Regulation

This review describes our knowledge of biotin transport in the small intestine of humans and other mammals and presents recent findings in the area. Previous studies have shown that biotin transport across the brush border membrane of the small intestinal absorptive cells occurs via a carrier-mediated, Na gradientdependent, electroneutral mechanism. Exit of biotin out of the enterocyte, i.e., t...

متن کامل

Role of Molecular Interactions and Oligomerization in Chaperone Activity of Recombinant Acr from Mycobacterium tuberculosis

Background: The chaperone activity of Mycobacterium tuberculosis Acr is an important function that helps to prevent misfolding of protein substrates inside the host, especially in conditions of hypoxia. Objectives: The aim of this study was to establish the correlation of structure and function of recombinant Acr proteins both before and after ge...

متن کامل

prevalence of Mycobacterium tuberculosis in patients infected with HIV by microscopical and molecular methods

Background:In some countries, one of the first and most common manifestations of HIV positive patients is tuberculosis (TB). HIV positive people are prone to other infections such as tuberculosis due to immune deficiency and reduced CD4+ cell count. Although increasing access to antiretroviral therapy has led to a reduction in HIV-related opportunistic infections and mortality, the simultaneous...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Protein & Cell

سال: 2011

ISSN: 1674-800X,1674-8018

DOI: 10.1007/s13238-011-1100-8